High affinity copper uptake protein 1
WebAntigen: High affinity copper uptake protein 1 Available to For-Profits: Yes Antigen Species: Human Hybridoma Cells Available (Non-Profit): No Isotype: MIgG2b Depositor: Clinical Proteomics Technologies for Cancer Host Species: mouse Antigen Sequence: Positive Tested Species Reactivity: Human Depositors Institution: National Cancer Institute Web27 de mar. de 2024 · The high-affinity Cu transporter Ctr1 ( Km ≈ 2 μM) 4, an integral membrane protein localized to the plasma membrane and endosomal vesicles, mediates cellular Cu uptake in eukaryotes from...
High affinity copper uptake protein 1
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Web19 de out. de 2024 · HD is a neurodegenerative disorder, caused by a dominant polyglutamine expansion within the N-terminus of the huntingtin protein and is characterized by oxidative stress and striatal degeneration. 63 In the striatum of HD brains, high Cu and iron concentrations have been detected. 64 Studies by Fox and colleagues (2007) have … Web16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper …
Web11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and transformed this mutant allele [COPT1(M44A)] into S. cerevisiae ctr1Δctr3Δ strain which lacks high affinity copper transporters CTR1 and CTR3 and cannot grow on … WebLOC105369026 high affinity copper uptake protein 1 [] Gene ID: 105369026, updated on 13-Feb-2024. Summary Other designations. high affinity ...
WebProtein target information for High affinity copper uptake protein 1 (Sumatran orangutan). Find diseases associated with this biological target and compounds tested against it in … WebHigh affinity copper uptake protein 1 is a protein that in humans is encoded by the SLC31A1 gene.[5][6] For faster navigation, this Iframe is preloading the Wikiwand page …
WebThese high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights into how cells acquire and regulate this essential nutrient. The …
Web8 de jul. de 1997 · We propose this gene as a candidate for high-affinity copper uptake in humans and by analogy have named it h CTR1. The hCTR1 and yeast CTR1 predicted transmembrane proteins are 29% identical, but the human protein is substantially smaller in both the extracellular metal-binding and intracellular domains. earthwise beauty marshmallow cleanserWeb1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... earthwise bp91001 batteryWeb23 de out. de 2009 · The protein responsible for copper entry from the circulation in most human cells is hCTR1, a small protein (190 amino acid residues) that functions as a … ct sandwellWebLOC106152599 high affinity copper uptake protein 1 [] Gene ID: 106152599, updated on 10-May-2024. Summary Other designations. high affinity ... cts angersHigh affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais earthwise blue sherwin williamsWeb1 de out. de 2002 · Protein High affinity copper uptake protein 1 Gene Slc31a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 196 … cts-anlægWeb11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and … earthwise battery pack bl80204